BT2301 BIOINFORMATICS - I SYLLABUS | ANNA UNIVERSITY B.TECH. BIOTECHNOLOGY 5TH SEMESTER SYLLABUS REGULATION 2008 2011 2012-2013 BELOW IS THE ANNA UNIVERSITY FIFTH SEMESTER B.TECH. BIOTECHNOLOGY DEPARTMENT SYLLABUS, TEXTBOOKS, REFERENCE BOOKS, IT IS APPLICABLE FOR ALL STUDENTS ADMITTED IN THE YEAR 2011 2012-2013 (ANNA UNIVERSITY CHENNAI,TRICHY,MADURAI,TIRUNELVELI,COIMBATORE), 2008 REGULATION OF ANNA UNIVERSITY CHENNAI AND STUDENTS ADMITTED IN ANNA UNIVERSITY CHENNAI DURING 2009
BT2301 BIOINFORMATICS - I L T P C
3 0 0 3
AIM
This course aims to develop the skills of the students in Bioinformatics. This is a prerequisite
for certain elective courses offered in the subsequent semesters & for project
work.
OBJECTIVES
At the end of this course, the students would have learnt about tools used in Bio
informatics & how to use them. This will facilitate the students to undertake projects
in the modern biology.
UNIT I INTRODUCTION 9
Basic UNIX commands – telnet – ftp – protocols – hardware – topology -search engines
– search algorithms – Perl programming.
UNIT II DATABASES 9
Data management – data life cycle – database technology – interfaces and
implementation – biological databases and their uses
UNIT III PATTERN MATCHING & MACHINE LEANING 9
Pairwise sequence alignment – local vs. global alignment – multiple sequence alignment
– dot matrix analysis – substitution matrices – dynamic programming – bayesian
methods – tools – BLAST – FASTA- machine learning – neural networks – statistical
methods – Hidden Markov models – Homology Modeling.
UNIT IV PHYLOGENY 9
Introduction; mutations; irrelevant mutations; controls; mutations as a measure of time;
distances; reconstruction; distances between species; estimating time intervals from
distances.
UNIT V ADVANCED TOPICS IN BIOINFORMATICS 9
Biomolecular and cellular computing – micro array analysis – systems biology.
TOTAL : 45 PERIODS
TEXT BOOKS
1. B. Bergeron, Bioinformatics Computing, PHI, 2002.
2. Westhead, D.R., Parish, J.H., Twyman, R.M., Instant Notes In Bioinformatics, BIOS
Scientific Publishers, 2000.
REFERENCE
1. C. Gibas & P. Jambeck, Developing Bioinformatics Skills, O'Reilly, 1999.
BT2301 BIOINFORMATICS - I L T P C
3 0 0 3
AIM
This course aims to develop the skills of the students in Bioinformatics. This is a prerequisite
for certain elective courses offered in the subsequent semesters & for project
work.
OBJECTIVES
At the end of this course, the students would have learnt about tools used in Bio
informatics & how to use them. This will facilitate the students to undertake projects
in the modern biology.
UNIT I INTRODUCTION 9
Basic UNIX commands – telnet – ftp – protocols – hardware – topology -search engines
– search algorithms – Perl programming.
UNIT II DATABASES 9
Data management – data life cycle – database technology – interfaces and
implementation – biological databases and their uses
UNIT III PATTERN MATCHING & MACHINE LEANING 9
Pairwise sequence alignment – local vs. global alignment – multiple sequence alignment
– dot matrix analysis – substitution matrices – dynamic programming – bayesian
methods – tools – BLAST – FASTA- machine learning – neural networks – statistical
methods – Hidden Markov models – Homology Modeling.
UNIT IV PHYLOGENY 9
Introduction; mutations; irrelevant mutations; controls; mutations as a measure of time;
distances; reconstruction; distances between species; estimating time intervals from
distances.
UNIT V ADVANCED TOPICS IN BIOINFORMATICS 9
Biomolecular and cellular computing – micro array analysis – systems biology.
TOTAL : 45 PERIODS
TEXT BOOKS
1. B. Bergeron, Bioinformatics Computing, PHI, 2002.
2. Westhead, D.R., Parish, J.H., Twyman, R.M., Instant Notes In Bioinformatics, BIOS
Scientific Publishers, 2000.
REFERENCE
1. C. Gibas & P. Jambeck, Developing Bioinformatics Skills, O'Reilly, 1999.
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