PY3301 PHARMACEUTICAL CHEMISTRY SYLLABUS | ANNA UNIVERSITY B.TECH. PHARMACEUTICAL TECHNOLOGY 5TH SEMESTER SYLLABUS REGULATION 2008 2011 2012-2013 BELOW IS THE ANNA UNIVERSITY FIFTH SEMESTER B.TECH. PHARMACEUTICAL TECHNOLOGY DEPARTMENT SYLLABUS, TEXTBOOKS, REFERENCE BOOKS, IT IS APPLICABLE FOR ALL STUDENTS ADMITTED IN THE YEAR 2011 2012-2013 (ANNA UNIVERSITY CHENNAI,TRICHY,MADURAI,TIRUNELVELI,COIMBATORE), 2008 REGULATION OF ANNA UNIVERSITY CHENNAI AND STUDENTS ADMITTED IN ANNA UNIVERSITY CHENNAI DURING 2009
PY3301 PHARMACEUTICAL CHEMISTRY
UNIT I PHYSICO-CHEMICAL PROPERTIES ON BIOLOGICAL ACTION OF
DRUGS 9
Physical properties – Optical isomers – Geometric isomers – Bioisosterism – Receptors
– Occupational theory – Affinity theory.
UNIT II AUTONOMIC AND CENTRAL NERVOUS SYSTEM ACTING DRUGS 9
Structure – Synthesis – Uses – Pilocarpine – Neostigmine – Propanthallene –
Salbutamol – Amphetamine – Phenoxy benzamine – Tolazoline – Thiopentone –
Diazepam – Chlorpromazine – Haloperidol.
UNIT III CARDIOVASCULAR AND RESPIRATORY SYSTEM ACTING DRUGS 9
Synthesis – Uses – Digoxin – Digitoxin – Procainamide – Diltiazem – Isosorbide dinitrate
– Captopril – Frusemide – Lovastatin – Clofibrate.
UNIT IV ANTIMICROBIAL AGENTS 9
Preparation – Therapeutic uses – Cephalosporine – Silver Sulphadiazine –
Cotrimoxazole – Roxithromycin – Isoniazid – Pyrazinamide – Dapsone – Clofazimine –
Idoxuridine – Zidovudine – Quinine – Primaquine – Cyclophosphamide – Methotrexate –
Griseofulvin.
UNIT V PERIPHERAL NERVOUS SYSTEM AND GASTROINTESTINAL
DRUGS 12
Structure – Synthesis – Uses – Gallamin triethiodide – Dantrolene Sodium – Ranitidine –
Omeprazole – Metronidazole – Cinnarizine – Dicyclomine – Bisacodyl.
L: 45 T: 15 TOTAL: 60 PERIODS
TEXTBOOKS
1. Ilango, K. and Valentina, P., “Text Book of Medicinal Chemistry”, Vol. I, 1st
Edition, Keerthi Publishers, 2007.
2. Kadam, S.S., Mahadik, K.R. and Bothara, K.G., “Principles of Medicinal
Chemistry”, Vol. I and II, Nirali Prakashan Publications, 1997.
REFERENCES
1. Chatwal, G., “Organic Chemistry of Natural Products”, Vol. I and II, 3rd Edition,
Himalaya Publishing House, 2002.
2. Wolff, M.E., “Burgers: Medicinal Chemistry”, Vol. I to VI, 5th Edition, John Willy
and Sons, 2005.
3. Bentley and Driver’s “Text Book of Pharmaceutical Chemistry”, 8th Edition,
Oxford University Press, 2002.
PY3301 PHARMACEUTICAL CHEMISTRY
UNIT I PHYSICO-CHEMICAL PROPERTIES ON BIOLOGICAL ACTION OF
DRUGS 9
Physical properties – Optical isomers – Geometric isomers – Bioisosterism – Receptors
– Occupational theory – Affinity theory.
UNIT II AUTONOMIC AND CENTRAL NERVOUS SYSTEM ACTING DRUGS 9
Structure – Synthesis – Uses – Pilocarpine – Neostigmine – Propanthallene –
Salbutamol – Amphetamine – Phenoxy benzamine – Tolazoline – Thiopentone –
Diazepam – Chlorpromazine – Haloperidol.
UNIT III CARDIOVASCULAR AND RESPIRATORY SYSTEM ACTING DRUGS 9
Synthesis – Uses – Digoxin – Digitoxin – Procainamide – Diltiazem – Isosorbide dinitrate
– Captopril – Frusemide – Lovastatin – Clofibrate.
UNIT IV ANTIMICROBIAL AGENTS 9
Preparation – Therapeutic uses – Cephalosporine – Silver Sulphadiazine –
Cotrimoxazole – Roxithromycin – Isoniazid – Pyrazinamide – Dapsone – Clofazimine –
Idoxuridine – Zidovudine – Quinine – Primaquine – Cyclophosphamide – Methotrexate –
Griseofulvin.
UNIT V PERIPHERAL NERVOUS SYSTEM AND GASTROINTESTINAL
DRUGS 12
Structure – Synthesis – Uses – Gallamin triethiodide – Dantrolene Sodium – Ranitidine –
Omeprazole – Metronidazole – Cinnarizine – Dicyclomine – Bisacodyl.
L: 45 T: 15 TOTAL: 60 PERIODS
TEXTBOOKS
1. Ilango, K. and Valentina, P., “Text Book of Medicinal Chemistry”, Vol. I, 1st
Edition, Keerthi Publishers, 2007.
2. Kadam, S.S., Mahadik, K.R. and Bothara, K.G., “Principles of Medicinal
Chemistry”, Vol. I and II, Nirali Prakashan Publications, 1997.
REFERENCES
1. Chatwal, G., “Organic Chemistry of Natural Products”, Vol. I and II, 3rd Edition,
Himalaya Publishing House, 2002.
2. Wolff, M.E., “Burgers: Medicinal Chemistry”, Vol. I to VI, 5th Edition, John Willy
and Sons, 2005.
3. Bentley and Driver’s “Text Book of Pharmaceutical Chemistry”, 8th Edition,
Oxford University Press, 2002.
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